Once Strike #1 is in the air, you can get him targeted quite easily.

You can do this through the Unit Orders Menu as well:

The rest is in the hands of the pilot, he will proceed directly to the target, adopt a suitable attack profile, and drop the bombs. He should get there in about 15 min of game time so you can speed up time with the "+" key, remembering to slow it down as he approaches the target using the "-" key or drop it to 1:1 time compression with the "ENTER" key. You can always hit the "SPACE BAR" to pause and restart the timer.